"At the Center for BioMolecular Modeling (CBM), teachers truly do come first. We work closely with talented science educators from across the USA to create innovative instructional materials that make the molecular world real for students.
We believe that the invisible world of molecules becomes real when students have an opportunity to hold physical models in their hands. This is true for flexible models made from Toobers, or accurate models made by rapid prototyping technologies. In both cases, the physical models function as thinking tools that stimulate questions that are then addressed using computer visualization tools."
Here are several links to websites that contain DNA "origami" exercises. Most of the information can be downloaded as a PDF.